Action of nicotine on sympathetic ganglia

Selective action of anesthetics on synapses and axons in mammalian sympathetic ganglia.

ANESTHETIC SUBSTANCES, in suitable concentrations, depress certain functions of the central nervous system, while leaving relatively unimpaired the capacity for activity in sensory nerve endings, peripheral nerve fibers, and various effector organs. In order to explain this selective action on the central nervous system it is usually assumed that synaptic mechanisms are more readily modified by...

The Effect of Endotoxin on Abdominal Sympathetic Ganglia.

The notion is an old one that diarrheas of infectious origin might be caused by the action of a toxin on the neurovegetative periphery. However, their site of action within the autonomic nervous system remains in dispute as does the importance which should be ascribed to this mechanism. Experimentally, Moreau (1868) produced what was called "paralytic hypersecretion of the succus entericus" by ...

Modulation of Synaptic Amplification in Sympathetic Ganglia

Dopamine as a synaptic transmitter and modulator in sympathetic ganglia: a different mode of synaptic action.

An analysis of the role of adrenergic transmission in mediating the hyperpolarizing, slow inhibitory postsynaptic potential has revealed that dopamine is apparently the specific synaptic transmitter for this response. An additional action of dopamine was discovered, namely the selective facilitation of another synaptic response, the slow excitatory postsynaptic potential. (This potential is a d...

Slow synaptic transmission in frog sympathetic ganglia.

Bullfrog ganglia contain two classes of neurone, B and C cells, which receive different inputs and exhibit different slow synaptic potentials. B cells, to which most effort has been directed, possess slow and late slow EPSPs. The sEPSP reflects a muscarinic action of acetylcholine released from boutons on B cells, whereas the late sEPSP is caused by a peptide (similar to teleost LHRH) released ...